Structure Therapeutics Inc.

601 Gateway Blvd., Suite 900

South San Francisco, CA 94080


November 27, 2023




U.S. Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549


Attn:Joshua Gorsky


Re: Structure Therapeutics Inc.
  Registration Statement on Form S-1
  Filed November 17, 2023
  File No. 333-275651
  Acceleration Request
  Requested Date: November 29, 2023
  Requested Time: 4:00 p.m. Eastern Time


Ladies and Gentlemen:


Pursuant to Rule 461 under the Securities Act of 1933, as amended, Structure Therapeutics Inc. hereby requests that the U.S. Securities and Exchange Commission accelerate the effective date of the above-referenced Registration Statement on Form S-1 (the “Registration Statement”) and declare the Registration Statement effective as of 4:00 p.m. Eastern Time, on November 29, 2023, or as soon thereafter as practicable.


Once the Registration Statement has been declared effective, please orally confirm that event with Patrick Loofbourrow of Cooley LLP at (619) 840-4824, or in his absence, Carlos Ramirez of Cooley LLP at (858) 550-6157.




Structure Therapeutics Inc.


By: /s/ Raymond Stevens  
  Raymond Stevens, Ph.D.  
  Chief Executive Officer